Tehran University of Medical Sciences Journal of Biostatistics and Epidemiology 2383-4196 9 4 2023 12 15 396 411 EN Arefeh Dehghani tafti Department of Biostatistics and Epidemiology, Faculty of Public Health, Kerman University of Medical Sciences, Kerman, Iran Yunes Jahani Department of Biostatistics and Epidemiology, Faculty of Public Health, Kerman University of Medical Sciences, Kerman, Iran Sara Jambarsang Department of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Abbas Bahrampour Department of Biostatistics and Epidemiology, Faculty of Public Health, Kerman University of Medical Sciences, Kerman, Iran 2024 03 02 2024 06 09  In the last few decades, in many research fields, different methods were introduced to discover groups with the same trends in longitudinal data. The clustering process is an unsupervised learning method, which classifies longitudinal data based on different criteria by performing algorithms. The current study was performed with the aim of reviewing various methods of longitudinal data clustering, including two general categories of non-parametric methods and model-based methods. PubMed, SCOPUS, ISI, Ovid, and Google Scholar were searched between 2000 and 2021. According to our systematic review, the non-parametric k-means Clustering Method utilizing Euclidean distance emerges as a leading approach for clustering longitudinal data This research, with an overview of the studies done in the field of clustering, can help researchers as a toolbox to choose various methods of longitudinal data clustering in idea generation and choosing the appropriate method in the classification and analysis of longitudinal data. https://jbe.tums.ac.ir/index.php/jbe/article/view/1393