Tehran University of Medical Sciences Journal of Biostatistics and Epidemiology 2383-4196 3 3/4 2018 07 11 83 87 EN Bahar Heydarnia Department of General Medicine, School of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran Mahmoud Mahmoudi Dpartment of Health Services Administration, Science and Research Branch, Islamic Azad University, Tehran, Iran Alireza Teimour Department of Neurosurgery, School of Medicine AND Bou Ali Hospital, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran Hesam Abdolhoseinpour Department of Neurosurgery, School of Medicine AND Bou Ali Hospital, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran 2018 03 06 2018 07 11 Background & Aim: Quality of life (QOL) is one of the important health components, indicating physical, social, and mental health. Vertebral fracture causes acute and chronic low back pain (LBP), physical disability and decreased QOL, and kyphoplasty is one of the effective methods for treating these types of fractures. Methods & Materials: This descriptive cross-sectional study was performed on 48 patients with vertebral fractures who referred for kyphoplasty surgery. Data were collected using two questionnaires, one including demographic information and the other consisting of 36 questions regarding QOL. Data was analyzed using chi-Square and Fisher’s exact tests in the SPSS software. P < 0.050 was considered as the significance level. Results:  Of  48  patients,  28  and  20  were  women  and  men,  respectively,  with  a  mean  age  of 64.12 ± 16.99 years. The mean QOL score of patients was 38.28 and 45.8% of the patients had moderate QOL. The mean score for physical and mental health subscales was 30.30 and 50.66, respectively. Conclusion: The mean of total score, the scores of 2 subscales of physical and mental health, and 8  dimensions  of  the  questionnaire  were  higher  among  men  compared  to  women.  There  were significant differences between the two sexes in 2 subscales of physical functioning and health-related disorder. The results of this study showed that LBP and physical dysfunction affected mental health of patients and psychiatric dimensions of the questionnaire. https://jbe.tums.ac.ir/index.php/jbe/article/view/164 https://jbe.tums.ac.ir/index.php/jbe/article/download/164/84