Tehran University of Medical Sciences Journal of Biostatistics and Epidemiology 2383-4196 4 4 2019 03 13 252 258 Mojtaba Sepandi Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran AND Department of Epidemiology and Biostatistics, Faculty of Health, Baqiyatallah University of Medical Sciences, Tehran, Iran. Maryam Taghdir Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran AND Department of Epidemiology and Biostatistics, Faculty of Health, Baqiyatallah University of Medical Sciences, Tehran, Iran. Isa Akarzadeh Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Farzad Khodamoradi Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Yousef Alimohamadi 3Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2018 11 23 Introduction: Depression is one of the main problems and disrupting daily life activities in women. Due to the important role of women in society and the effect of depression on this group activity the aims of the current study was to investigate of the identification effective factors on women's depression in Khuzestan province. Method: In this cross-sectional study, 899 women who referred to health centers in Ahwaz were selected by cluster sampling method. For analysis purpose, multivariate and univariate linear regression was used. All analysis performed by SPSS version 19 with regarding α: 0.05 for the significant level. Results: in case of effective factors on depression score, number of Education Years, Competence score, Relatedness score, Autonomy score, Presence of Meaning in Life score, Search for Meaning in Life score had the significant effect on depression score (p<0.001). Conclusion: Education level, marital status, education level, Social Competence, relatedness, Autonomy; Presence of meaning in life, Search for meaning in life and Depression are effective factors on depression so focusing on this factors can have the very important role in prevention programs. https://jbe.tums.ac.ir/index.php/jbe/article/view/224 https://jbe.tums.ac.ir/index.php/jbe/article/download/224/184