Tehran University of Medical Sciences Journal of Biostatistics and Epidemiology 2383-4196 2 1 2016 06 06 20 24 EN Ke-Sheng Wang Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN, USA. Xuefeng Liu Department of Systems Leadership and Effectiveness Science, School of Nursing, University of Michigan, Ann Arbor, MI, USA. 2016 06 06 2016 06 06 Background & Aim:A meta-analysis refers to the statistical synthesis of results from a series of studies and has been used to estimate pooled prevalence of human diseases. In this study, we review some statistical issues regarding the meta-analysis of the prevalence of human diseases such as statistical software and programs, transformations of prevalence rate, assessment of heterogeneity, and publication bias. https://jbe.tums.ac.ir/index.php/jbe/article/view/46 https://jbe.tums.ac.ir/index.php/jbe/article/download/46/36