Original Article

The Epidemiological, Risk Factors and Clinical Characteristics of Ischemic Stroke in Ardabil Province, Iran: a Hospital Based Study

Abstract

Introduction: Stroke is the third most common cause of death in world after heart diseases and cancer. Due to the higher rate of stroke and less attention to its occurrence, assessing the prevalence of ischemic brain stroke and its clinical patterns across countries and nations such as Iran could be valuable and important.
Objectives: The aim of this study was to assess the epidemiological, Risk factor and clinical characteristics of ischemic stroke in Ardabil province.
Materials and Methods: This descriptive cross-sectional study has been done on 676 patients with ischemic stroke who referred to Ardabil city hospital during at year 2018. Data collected by using a checklist including demographic and clinical data of patients. Collected data were analyzed by statistical methods in SPSS version 21. The p-value less than 0.05 was considered as significant.
Results: Of all patients, 294 (43.5%) were female and rest of them were male. The mean age of patients was 69.3±13.2 years. Of all patients, 25.3% arrived to the hospital in less than 4.5 hours. The difference between arrival time to the hospital in rural and urban patients was significant. The most risk factors were seen in both sexes was HTN and in female only was DM and in male only was CVA. The results of CT and MRI showed that 30% and 64.9% of patients had lesion respectively that of them the most lesion in MRI was SMALL VESSEL and in CT was Middle Cerebral Artery (MCA).
Conclusion: Results showed that the patients who live in urban areas arrive to emergency sooner than rural patients. The significant relation was seen between AF, residence place and valvular with arriving time to hospital.

1.Abbasi V, Fattahzadeh Ardalani GH, Safarneghad P. Albumin impact on clinical practice and complications of ischemic stroke in patients with stroke. International Journal of Basic & Clinical Pharmacology. 2016;5(5):2114-7.
2.Abbasi V, Amani F, Aslanian R, Hoseinkhani A, Zakeri A, Masoumi R. Epidemiological Study of Stroke in Ardabil, Iran: a Hospital Based-Study. J Neurol Disord Stroke. 2017;5(3):1128.
3. American Heart Association. Heart disease and stroken statistics—2011 update. Circulation 2011; 123(4):e18-209. doi: 10.1161/CIR.0b013e3182009701.
4. By Mayo Clinic Staff. Symptoms brain lesions and definition. Available form: https://www.mayoclinic.org/symptoms/brain-lesions/basics/definition.
5.Fahimfar N, Khalili D, Mohebi R, Azizi F, Hadaegh F. Risk factors for ischemic stroke; results from 9 years of follow-up in a population based cohort of Iran. BMC Neurol. 2012; 12: 117.
6. Abbasi, V., Atalu, A., Sharghi, A., Taghvatalab, F. A clinical study investigating the three months prognosis of patients with ischemic stroke treated with recombinant tissue plasminogen activator (rt-PA) and its effective factors. Journal of Emergency Practice and Trauma, 2019; 5(2): 47-50. doi: 10.15171/jept.2019.05
7.Sarsarshahi A, Boostani R, Sarsarshahi S, Kiani R. Evaluation of risk factors of patients with subarachnoid hemorrhage in Motahari Hospital of Urmia University (March 2002-March 2006). Med J Mashhad Univ Med Sci. 2007;50(4):367-70.
8.Talebi M, Ghertasi M, Taheraghdam A, Andalib S, Sharifipour E. A comparison of risk factors and severity of ischemic stroke in female and male genders in North-West Iran: A cross-sectional study. Iran J Neurol. 2014;13(4):215-9. [PubMed: 25632333]. [PubMed Central: PMC4300796].
9.Sabzghabaei A , Aeinechian S , Shojaee M, Kashani P, Manouchehrifar M. Epidemiological Features of Ischemic Brain Stroke; a Cross-Sectional Hospital-Based Study, Arch Neurosci. 2019 ; 6(2):e74362. doi: 10.5812/ans.74362.
10.Ahangar AA, Ashraf Vaghefi SB, Ramaezani M. Epidemiological evaluation of stroke in Babol, northern Iran (2001-2003). Eur Neurol. 2005;54(2):93-7. doi: 10.1159/000088643. [PubMed: 16195668].
11.Oveisgharan S, Sarrafzadegan N, Shirani S, Hosseini S, Hasanzadeh P, Khosravi A. Stroke in Isfahan, Iran: Hospital admission and 28-day case fatality rate. Cerebrovasc Dis. 2007;24(6):495-9. doi: 10.1159/000110418. [PubMed: 17971627].
12.Borhani-Haghighi A, Safari R, Heydari ST, Soleimani F, Sharifian M, Yektaparast Kashkuli S, et al. Hospital mortality associated with stroke in southern Iran. Iran J Med Sci. 2013;38(4):314-20. [PubMed: 24293785]. [PubMed Central: PMC3838983].
13.Sarrafzadegan N, Gharipour M, Sadeghi M, Nezafati P, Talaie M, Oveisgharan S, et al. Metabolic syndrome and the risk of ischemic stroke. J Stroke Cerebrovasc Dis. 2017;26(2):286-94. doi: 10.1016/j.jstrokecerebrovasdis.2016.09.019. [PubMed: 27769610].
14.Savadi Oskoui D, Aminisani N, Hashemilar M. Blood Lipids and Ischemic Stroke: A Case Control Study. J Ardabil Univ Med Sci. 2003; 3 (4) :27-31.
15. Chang YJ, Ryu SJ, Lin SK. Carotid artery stenosis in ischemic stroke patients with nonvalvular atrial fibrillation. Cerebrovasc Dis. 2002;13(1):16-20. doi: 10.1159/000047740. [PubMed: 11810005].
16.Tan TY, Chang KC, Liou CW, Schminke U. Prevalence of carotid artery stenosis in Taiwanese patients with one ischemic stroke. J Clin Ultrasound. 2005;33(1):1-4. doi: 10.1002/jcu.20081. [PubMed: 15690439].
17. Fernandes M, Keerthiraj B, Mahale AR, Kumar A, Dudekula A. Evaluation of carotid arteries in stroke patients using color Doppler sonography: A prospective study conducted in a tertiary care hospital in South India. Int J Appl Basic Med Res. 2016;6(1):38-44. doi: 10.4103/2229-516X.174007. [PubMed: 26958521]. [PubMed Central: PMC4765273].
18. He W, Liu Y, Feng J, Huang Q, Xu J, Liu X, Yu C, Zhu W, Wang T, Jin D, Liu H, Huang Y and Chen B (2018) The Epidemiological Characteristics of Stroke in Hunan Province, China. Front. Neurol. 9:583. doi: 10.3389/fneur.2018.00583.
Files
IssueVol 6 No 1 (2020) QRcode
SectionOriginal Article(s)
DOI https://doi.org/10.18502/jbe.v6i1.4759
Keywords
Risk factor; Epidemiology; Ischemia stroke; Ardabil

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Fattahzadeh-Ardalani G, Sharghi A, Atalu A, Noori F. The Epidemiological, Risk Factors and Clinical Characteristics of Ischemic Stroke in Ardabil Province, Iran: a Hospital Based Study. JBE. 2020;6(1):52-61.